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{"id":158,"date":"2015-07-31T14:12:24","date_gmt":"2015-07-31T14:12:24","guid":{"rendered":"http:\/\/www.verhelstlab.net\/?p=158"},"modified":"2016-11-24T16:54:40","modified_gmt":"2016-11-24T16:54:40","slug":"rhomboid-abpp","status":"publish","type":"post","link":"http:\/\/www.verhelstlab.net\/rhomboid-abpp\/","title":{"rendered":"Rhomboid ABPP"},"content":{"rendered":"<p>A new paper from our group in <a href=\"http:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acschembio.5b00514\" target=\"_blank\">ACS Chemical Biology<\/a> about inhibitor fingerprinting of rhomboid proteases by ABPP. For the first time, a wide variety of rhomboid proteases from 12 different organisms is screened against a set of the same small molecules. Besides inhibitors that display certain selectivity, it was found that some bacterial rhomboids autoprocess themselves.<\/p>\n<p><a href=\"http:\/\/www.verhelstlab.net\/wp-content\/uploads\/2015\/07\/ACSChemBiol2015.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.verhelstlab.net\/wp-content\/uploads\/2015\/07\/ACSChemBiol2015.jpg\" alt=\"ACSChemBiol2015\" width=\"500\" height=\"253\" class=\"aligncenter size-full wp-image-159\" srcset=\"http:\/\/www.verhelstlab.net\/wp-content\/uploads\/2015\/07\/ACSChemBiol2015.jpg 500w, http:\/\/www.verhelstlab.net\/wp-content\/uploads\/2015\/07\/ACSChemBiol2015-300x152.jpg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new paper from our group in ACS Chemical Biology about inhibitor fingerprinting of rhomboid proteases by ABPP. For the first time, a wide variety of rhomboid proteases from 12 different organisms is screened against a set of the same <span class=\"excerpt-dots\">&hellip;<\/span> <a class=\"more-link\" href=\"http:\/\/www.verhelstlab.net\/rhomboid-abpp\/\"><span class=\"more-msg\">Continue reading &rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":40,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-158","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/posts\/158","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/comments?post=158"}],"version-history":[{"count":1,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/posts\/158\/revisions"}],"predecessor-version":[{"id":160,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/posts\/158\/revisions\/160"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/media\/40"}],"wp:attachment":[{"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/media?parent=158"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/categories?post=158"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.verhelstlab.net\/wp-json\/wp\/v2\/tags?post=158"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}